It has passed over a decade since the establishment of iPS cells (induced Pluripotent Stem cells). Studies on clinical applications of a variety of tissue stem cells in the field of regenerative medicine have exponentially increased. However, strict quality control of the tissue stem cells is the most importantly required task for clinical treatment in safe, so as the mechanism of re-programing and gene regulation in early embryonic development has not been fully understood yet.
In the present report, I’d like to provide examples of evidence of chromosome instabilities in the established tissue stem cell lines, such as in cases of an ES cell line derived from crab-eating monkey, human iPS cell lines and cord blood derived mesenchymal stem cells.
Taken together from the results of above mentioned data and knowledge from recent literatures, I hope to discuss with the usefulness of karyotyping especially in its early passage of the establishment in order to guarantee the qualities of the stem cells.
It has passed over a decade since the establishment of iPS cells (induced Pluripotent Stem cells). Studies on clinical applications of a variety of tissue stem cells in the field of regenerative medicine have exponentially increased. However, strict quality control of the tissue stem cells is the most importantly required task for clinical treatment in safe, so as the mechanism of re-programing and gene regulation in early embryonic development has not been fully understood yet.
In the present report, I’d like to provide examples of evidence of chromosome instabilities in the established tissue stem cell lines, such as in cases of an ES cell line derived from crab-eating monkey, human iPS cell lines and cord blood derived mesenchymal stem cells.
Taken together from the results of above mentioned data and knowledge from recent literatures, I hope to discuss with the usefulness of karyotyping especially in its early passage of the establishment in order to guarantee the qualities of the stem cells.
2B7 - Building 2 GSA2018_APCC6 GSACC62018@canberra.edu.auTechnical Issues?
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